EXACLAV-1.2 INJECTION
COMBIPACK OF AMOXICILLIN AND POTASSIUM CLAVULANATE INJECTION BP 1.2 GM AND STERILISED WATER FOR INJECTIONS BP 20 ML
Amoxicillin Sodium belongs to the group of medicines known as penicillin antibiotics. Potassium Clavulanate is a semisynthetic beta-lactamase inhibitor isolated from Streptomyces. The chemical name for Amoxicillin Sodium is sodium; (2S,5R,6R) 6-[[(2R)-2-amino-2- (4-hydroxyphenyl) acetyl]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylate, its molecular formula is C16H18N3NaO5S; its molecular weight is 387.386 g/mol. The chemical name for Potassium Clavulanate is Potassium; (2R,3Z,5R)-3- (2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo [3.2.0]heptane-2-carboxylate, its molecular formula is C8H8KNO5; its molecular weight is 237.252 g/mol.
INDICATIONS FOR USE
- EXACLAV-1.2 INJECTION is indicated for the treatment of the following infections in adults and children:
- Severe infections of the ear, nose and throat (such as mastoiditis, peritonsillar infections, epiglottitis and sinusitis when accompanied by severe systemic signs and symptoms)
- Acute exacerbations of chronic bronchitis (adequately diagnosed)
- Community acquired pneumonia
- Cystitis
- Pyelonephritis
- Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis.
- Bone and joint infections, in particular osteomyelitis
- Intra-abdominal infections
- Female genital infections
PROPHYLAXIS AGAINST INFECTIONS ASSOCIATED WITH MAJOR SURGICAL PROCEDURES IN ADULTS, SUCH AS THOSE INVOLVING THE
- Gastrointestinal tract
- Pelvic cavity
- Head and neck
- Biliary tract surgery
- Consideration should be given to the official guidance on the appropriate use of antibacterial agents.
