OMEALERT OMEPRAZOLE CAPSULES 20MG
COMPOSITION
- Each hard gelatin capsule contains:
- Omeprazole BP 20 mg (As enteric coated granules)
- Excipients q.s.
- Empty Hard gelatin capsule contains approved colours.
ACTION
Omeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit ant cholinergic of H2 histamine antagonistic properties, that do not exhibit antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H+/K+ ATP ase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa. Omeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.
INDICATION
Omeprazole capsules are indicated for short-term treatment of active duodenal ulcer, of active beingn gastric ulcer, of erosive esophagi is which has been diagnosed by endoscopy. Omeprazole capsules are indicated to maintain healing of erosive esophagitis, which has been diagnosed by endoscopy. Omeprazole capsules ate indicated to maintain healing of erosive esophagitis, for the long-treatment of pathological hypersecretory conditions (e.g; Zollinger-Ellison Syndrome, multiple endocrine adenomas and systemic mastocytosis).
CONTRAINDICATIONS
Hypersensitivity to Omperazole, Risk-benefit should be considered if current of history of chronic hepatic disease exists. Dosage reduction may be required due to increased half-life in chronic hepatic disease.
